Detection of Human Protein Structures by Select Deep Learning Models and Dynamic Systems

Abstract

Peptide bonds bind amino acids together to form proteins. Because of the way amino acids fold, proteins have a three-dimensional structure. Increased data, or samples, improves machine learning models that learn from examples. ANNs, a single-layer learning system, require sophisticated systems and time to learn massive volumes of data over time. Today, the multi-layer deep learning technique is preferred. Deep learning uses artificial neural networks. This part of the work provides technical details about the deep learning methods used. This research's deep learning methods include CNN, Hidden Markov Model (HMM), Recurrent Weighted Average (RWA), and Conditional Random Fields (CRF). The training and testing results of these models are presented in this work. For this work, the CNN, HMM, RWA, and CRF algorithms were all compared using the CB513 dataset. In addition, each method was analyzed and contrasted with other research conducted previously. In this particular research endeavour, the respective success rates of the four models that were built for predicting the protein secondary structure were as follows: 82.54%, 81.06%, 81.10%, and 81.48%. The models and working environment produced in this study can be used to predict protein secondary structure quickly. In deep learning experiments, data amount affects learning. Increasing data will test the study's models.