Meta analysis and comprehensive study of Impact of Early pregnancy Hypertension
Abstract
The primary aim of this research was to gather more detailed information regarding the potential impacts of high maternal blood pressure early in pregnancy.;
To achieve this objective, our study utilized a comprehensive methodology. We randomly distributed questionnaires to a sample of one thousand individuals and accessed several medical databases including CNKI, Wanfang Data, CQVIP, CBM, PubMed, Embase, The Biomedical and Pharmacology Abstracts Database, and CMCC to review cohort studies exploring the effects of high blood pressure in pregnancy. A random-effects model was employed to estimate odds ratios (ORs) and establish 95% confidence intervals (CIs) for various pregnancy outcomes.
Our results highlighted significant risks associated with high blood pressure during the early pregnancy stages. The conditions influenced include preeclampsia, gestational diabetes mellitus, preterm birth, stillbirth, Cesarean delivery, the need for neonatal intensive care, placental abruption, HELLP syndrome, being small for gestational age (SGA), and miscarriages across all trimesters. Notably, even pre-hypertension was found to significantly increase the likelihood of these outcomes, except for stillbirth, with risk levels intensifying with greater severity of hypertension
The study strongly indicates the necessity for enhanced monitoring of maternal blood pressure, particularly when the mother exhibits pre-hypertensive symptoms. Early identification and management of high blood pressure may mitigate the risk of several severe pregnancy complications. This underscores the urgency of integrating comprehensive blood pressure checks into prenatal care routines to improve maternal and neonatal health outcomes.
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Data Availability Statement
The data used to support the findings of this study are included within the article.
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