The Role of Consanguinity, Blood group, and Hemoglobin Levels in Beta Thalassemia Vulnerability

Abstract

The present study project aims to investigate the relationship of β-thalassemia with Consanguinity, Blood group, and Hemoglobin Levels of both gender (male and female), in Saladin Governorate. Variables grouping of (n=100) β-thalassemia patients was performed. The current study is conducted to cover a period of six months. In total 100 patients diagnosed with Beta thalassemia were enrolled. They were divided into two groups, patients in Group I (n = 50) of male and those in Group II (n = 50) of female. The observed consanguinity pattern in both genders was non consanguinity>Cousin, while the observed ABO blood group patterns in male patients were O+>A+>B+>AB+& O-, yet the ABO blood group pattern in the females was O⁺ >A⁺> O^->AB⁺>B⁺. As well as, Hb levels in the 10-20 age groups were lower than in the other age groups studied.,The study came with conclusion that β-thalassemia patients tend to show a higher frequency of the A+ blood group and the lowest frequency of O- blood group; while consanguinity had no effect on the incidence of beta thalassemia.